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1

Prevention of toxic epidermal necrolysis by regulatory T cells

Hiroaki Azukizawa, Shigetoshi Sano, Hiroshi Kosaka, Yasuyuki Sumikawa, Satoshi Itami

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 287 KB

english, 2005

2

Efficacy of additional i.v. immunoglobulin to steroid therapy in Stevens-Johnson syndrome and toxic epidermal necrolysis

Aihara, Michiko, Kano, Yoko, Fujita, Hiroyuki, Kambara, Takeshi, Matsukura, Setsuko, Katayama, Ichiro, Azukizawa, Hiroaki, Miyachi, Yoshiki, Endo, Yuichiro, Asada, Hideo, Miyagawa, Fumi, Morita, Eishi

Journal:

The Journal of Dermatology

Year:

2015

Language:

english

File:

PDF, 876 KB

english, 2015

3

Drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms or non‐drug‐related erythroderma with a persistent human herpesvirus 6 infection

Mitsui, Yasuhiro, Ogawa, Kohei, Miyagawa, Fumi, Azukizawa, Hiroaki, Yoshikawa, Tetsushi, Asada, Hideo

Journal:

The Journal of Dermatology

Year:

2019

Language:

english

File:

PDF, 312 KB

english, 2019

4

ChemInform Abstract: 2-Acyl-tetrahydroisoquinoline-3-carboxylic Acids: Lead Compounds with Triple Actions, Peroxisome Proliferator-Activated Receptor α/γ Agonist and Protein-Tyrosine Phosphatase 1B Inhibitory Activities.

Kazuya Otake, Satoru Azukizawa, Kenji Takahashi, Masaki Fukui, Michiko Shibabayashi, Hikaru Kamemoto, Masayuki Kasai, Hiroaki Shirahase

Journal:

Year:

2012

File:

PDF, 23 KB

2012

5

ChemInform Abstract: A Novel Series of (S)-2,7-Substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor α/γ Dual Agonists with Protein-Tyrosine Phosphatase 1B Inhibitory Activity.

Kazuya Otake, Satoru Azukizawa, Masaki Fukui, Michiko Shibabayashi, Hikaru Kamemoto, Tomohiro Miike, Kazuyoshi Kunishiro, Masayasu Kasai, Hiroaki Shirahase

Journal:

Year:

2012

File:

PDF, 22 KB

2012

6

Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes

Hiroaki Azukizawa, Hiroshi Kosaka, Shigetoshi Sano, William R. Heath, Isao Takahashi, Xing-Hua Gao, Yasuyuki Sumikawa, Masaru Okabe, Kunihiko Yoshikawa, Satoshi Itami

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 392 KB

english, 2003

7

Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells

Hiroaki Azukizawa, Anja Döhler, Nobuo Kanazawa, Arnab Nayak, Martin Lipp, Bernard Malissen, Ingo Autenrieth, Ichiro Katayama, Marc Riemann, Falk Weih, Friederike Berberich-Siebelt, Manfred B. Lutz

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 659 KB

english, 2011

8

Induction of β-defensin 3 in keratinocytes stimulated by bacterial lipopeptides through toll-like receptor 2

Yasuyuki Sumikawa, Hideo Asada, Katsuaki Hoshino, Hiroaki Azukizawa, Ichiro Katayama, Shizuo Akira, Satoshi Itami

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 622 KB

english, 2006

9

Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabeticdb/dbmice—possible dysfunction of receptor and/or receptor–G protein coupling

Tomohiro Miike, Kazuyoshi Kunishiro, Mamoru Kanda, Satoru Azukizawa, Kazuyoshi Kurahashi, Hiroaki Shirahase

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2008

Language:

english

File:

PDF, 271 KB

english, 2008

10

Clinical implications of leukocytapheresis using a centrifugal cell separator for steroid-resistant pyoderma gangrenosum associated with inflammatory bowel disease

Takaaki HANAFUSA, Hiroaki AZUKIZAWA, Noriko UMEGAKI, Mamori TANI, Yuji YAMAGUCHI, Ichiro KATAYAMA

Journal:

The Journal of Dermatology

Year:

2011

Language:

english

File:

PDF, 383 KB

english, 2011

11

Animal models of toxic epidermal necrolysis

Hiroaki AZUKIZAWA

Journal:

The Journal of Dermatology

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

12

Revisiting the tolerogenicity of epidermal Langerhans cells

Lutz, Manfred B, Döhler, Anja, Azukizawa, Hiroaki

Journal:

Immunology & Cell Biology

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

13

Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: Peroxisome proliferator-activated receptor γ selective agonists with protein-tyrosine phosphatase 1B inhibition

Kazuya Otake, Satoru Azukizawa, Masaki Fukui, Kazuyoshi Kunishiro, Hikaru Kamemoto, Mamoru Kanda, Tomohiro Miike, Masayasu Kasai, Hiroaki Shirahase

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

14

Blockade of Interleukin-6 Receptor Alleviates Disease in Mouse Model of Scleroderma

Shun Kitaba, Hiroyuki Murota, Mika Terao, Hiroaki Azukizawa, Fumitaka Terabe, Yoshihito Shima, Minoru Fujimoto, Toshio Tanaka, Tetsuji Naka, Tadamitsu Kishimoto, Ichiro Katayama

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 2.72 MB

english, 2012

15

The predominant drug-specific T-cell population may switch from cytotoxic T cells to regulatory T cells during the course of anticonvulsant-induced hypersensitivity

Hanafusa, Takaaki, Azukizawa, Hiroaki, Matsumura, Sayaka, Katayama, Ichiro

Journal:

Journal of Dermatological Science

Year:

2012

Language:

english

File:

PDF, 764 KB

english, 2012

16

Evaluation of provocation test monitoring palmoplantar temperature with the use of thermography for diagnosis of focal tonsillar infection in palmoplantar pustulosis

Asada, Hideo, Miyagawa, Sachiko, Tamura, Manabu, Azukizawa, Hiroaki, Tanemura, Atsushi, Yamaguchi, Yuji, Sumikawa, Yasuyuki, Itami, Satoshi, Kubo, Takeshi, Yoshikawa, Kunihiko

Journal:

Journal of Dermatological Science

Year:

2003

Language:

english

File:

PDF, 450 KB

english, 2003

17

Development and Clinical Study of a Self-Dissolving Microneedle Patch for Transcutaneous Immunization Device

Sachiko Hirobe, Hiroaki Azukizawa, Kazuhiko Matsuo, You Zhai…

Journal:

Pharmaceutical Research

Year:

2013

Language:

english

File:

PDF, 635 KB

english, 2013

18

A Clinical study of influenza vaccine using a dissolving microneedle array

Azukizawa, Hiroaki, Hirobe, Sachiko, Hanafusa, Takaaki, Matsuo, Kazuhiko, Quan, Ying-Shu, Kamiyama, Fumio, Katayama, Ichiro, Okada, Naoki, Nakagawa, Shinsaku

Journal:

Journal of Dermatological Science

Year:

2013

Language:

english

File:

PDF, 58 KB

english, 2013

19

Analysis of B cell subsets in severe cutaneous adverse reaction

Hiroaki Azukizawa,Kenichi Kato,Ichiro Katayama

Journal:

Clinical and Translational Allergy

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

20

Immune reconstitution inflammatory syndrome in a patient with adult-onset Still’s disease: Graft-versus-host-like skin reaction with possible asymptomatic human herpes virus reactivation during steroid tapering

Kosuke Yamaga,Takaaki Hanafusa,Hiroaki Azukizawa…

Journal:

European Journal of Dermatology

Year:

2014

Language:

english

File:

PDF, 345 KB

english, 2014

21

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance

Baratin, Myriam, Foray, Chloe, Demaria, Olivier, Habbeddine, Mohamed, Pollet, Emeline, Maurizio, Julien, Verthuy, Christophe, Davanture, Suzel, Azukizawa, Hiroaki, Flores-Langarica, Adriana, Dalod, Ma

Journal:

Year:

2015

Language:

english

File:

PDF, 3.17 MB

english, 2015

22

Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch

Hirobe, Sachiko, Azukizawa, Hiroaki, Hanafusa, Takaaki, Matsuo, Kazuhiko, Quan, Ying-Shu, Kamiyama, Fumio, Katayama, Ichiro, Okada, Naoki, Nakagawa, Shinsaku

Journal:

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

23

Novel Functional Aspect of Antihistamines: The Impact of Bepotastine Besilate on Substance P-Induced Events

Kitaba, Shun, Murota, Hiroyuki, Yahata, Yoko, Azukizawa, Hiroaki, Katayama, Ichiro

Journal:

Journal of Allergy (Hindawi Publishing Corporation)

Year:

2009

Language:

english

File:

PDF, 6.62 MB

english, 2009

24

Antigen-Specific CD8 T Cells Can Eliminate Antigen-Bearing Keratinocytes with Clonogenic Potential via an IFN-γ-Dependent Mechanism

De Kluyver, Rachel L, Moritz, Linnea, Harris, Craig A, Azukizawa, Hiroaki, Frazer, Ian H

Journal:

The Journal of Investigative Dermatology

Year:

2010

Language:

english

File:

PDF, 424 KB

english, 2010

25

Barrier Abnormality Due to Ceramide Deficiency Leads to Psoriasiform Inflammation in a Mouse Model

Nakajima, Kimiko, Terao, Mika, Takaishi, Mikiro, Kataoka, Sayo, Goto-Inoue, Naoko, Setou, Mitsutoshi, Horie, Kyoji, Sakamoto, Fumiko, Ito, Masaaki, Azukizawa, Hiroaki, Kitaba, Shun, Murota, Hiroyuki,

Journal:

The Journal of Investigative Dermatology

Year:

2013

Language:

english

File:

PDF, 21.76 MB

english, 2013

26

Antigen-Specific CD4 Cells Assist CD8 T-Effector Cells in Eliminating Keratinocytes

Broom, Jennifer K, Lew, Andrew M, Azukizawa, Hiroaki, Kenna, Tony J, Leggatt, Graham R, Frazer, Ian H

Journal:

The Journal of Investigative Dermatology

Year:

2010

Language:

english

File:

PDF, 840 KB

english, 2010

27

B-1 B cell progenitors transiently and partially express keratin 5 during differentiation in bone marrow

Hanafusa, Takaaki, Kato, Kenichi, Azukizawa, Hiroaki, Miyazaki, Jun-ichi, Takeda, Junji, Katayama, Ichiro

Journal:

Journal of Dermatological Science

Year:

2015

Language:

english

File:

PDF, 2.45 MB

english, 2015

28

Peculiar Distribution of Tumorous Xanthomas in an Adult Case of Erdheim-Chester Disease Complicated by Atopic Dermatitis

Murakami, Yukako, Wataya-Kaneda, Mari, Terao, Mika, Azukizawa, Hiroaki, Murota, Hiroyuki, Nakata, Yukiko, Katayama, Ichiro

Journal:

Case Reports in Dermatology

Year:

2011

Language:

english

File:

PDF, 754 KB

english, 2011

29

In vitro screening of drug-reactive T-cells in mice

Kato, Kenichi, Azukizawa, Hiroaki, Hanafusa, Takaaki, Katayama, Ichiro

Journal:

Journal of Dermatological Science

Year:

2016

Language:

english

File:

PDF, 50 KB

english, 2016

30

Synthesis and Biological Evaluation of (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: A Novel Series of PPARγ Agonists

Azukizawa, Satoru, Kasai, Masayasu, Takahashi, Kenji, Miike, Tomohiro, Kunishiro, Kazuyoshi, Kanda, Mamoru, Mukai, Chisato, Shirahase, Hiroaki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

31

A Novel Series of (S)-2,7-Substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor α/γ Dual Agonists with Protein-Tyrosine Phosphatase 1B Inhibitory Activity

Otake, Kazuya, Azukizawa, Satoru, Fukui, Masaki, Shibabayashi, Michiko, Kamemoto, Hikaru, Miike, Tomohiro, Kunishiro, Kazuyoshi, Kasai, Masayasu, Shirahase, Hiroaki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2011

Language:

english

File:

PDF, 785 KB

english, 2011

32

Novel 2,7-Substituted (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor γ Partial Agonists with Protein–Tyrosine Phosphatase 1B Inhibition

Otake, Kazuya, Azukizawa, Satoru, Takeda, Shigemitsu, Fukui, Masaki, Kawahara, Arisa, Kitao, Tatsuya, Shirahase, Hiroaki

Year:

2015

Language:

english

File:

PDF, 982 KB

english, 2015

33

2-Acyl-tetrahydroisoquinoline-3-carboxylic Acids: Lead Compounds with Triple Actions, Peroxisome Proliferator-Activated Receptor α/γ Agonist and Protein-Tyrosine Phosphatase 1B Inhibitory Activities

Otake, Kazuya, Azukizawa, Satoru, Takahashi, Kenji, Fukui, Masaki, Shibabayashi, Michiko, Kamemoto, Hikaru, Kasai, Masayasu, Shirahase, Hiroaki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2011

Language:

english

File:

PDF, 499 KB

english, 2011

34

pentasomy X Mosaic in Two Adult Sisters with Diabetes Mellitus.

NAKANO, Shigeru, SASAME, Atsuko, AZUKIZAWA, Sadahide, KIGOSHI, Toshikazu, UCHIDA, Kenzo, TAKAHASHI, Hiroaki, MORIMOTO, Shinpei

Journal:

Internal Medicine

Year:

1992

Language:

english

File:

PDF, 522 KB

english, 1992

35

Impact of Sedative and Non-Sedative Antihistamines on the Impaired Productivity and Quality of Life in Patients with Pruritic Skin Diseases

Murota, Hiroyuki, Kitaba, Shun, Tani, Mamori, Wataya-Kaneda, Mari, Azukizawa, Hiroaki, Tanemura, Atsushi, Umegaki, Noriko, Terao, Mika, Kotobuki, Yorihisa, Katayama, Ichiro

Journal:

Allergology International

Year:

2010

Language:

english

File:

PDF, 371 KB

english, 2010

36

Successful treatment with gefitinib after Stevens–Johnson syndrome associated with afatinib therapy in a patient with adenocarcinoma of the lung

Otsuka, Tomoyuki, Tanaka, Aya, Azukizawa, Hiroaki, Sasaki, Shoko, Ishijima, Mikako, Matsuki, Takanori, Osa, Akio, Nakatani, Takeshi, Kuroyama, Muneyoshi, Hirata, Haruhiko, Kijima, Takashi

Journal:

International Cancer Conference Journal

Year:

2017

Language:

english

File:

PDF, 861 KB

english, 2017

37

Novel interferon-γ enzyme-linked immunoSpot assay using activated cells for identifying hypersensitivity-inducing drug culprits

Kato, Kenichi, Kawase, Asami, Azukizawa, Hiroaki, Hanafusa, Takaaki, Nakagawa, Yukinobu, Murota, Hiroyuki, Sakaguchi, Shimon, Asada, Hideo, Katayama, Ichiro

Journal:

Journal of Dermatological Science

Year:

2017

Language:

english

File:

PDF, 863 KB

english, 2017

38

The characteristics of patients with persistent HHV-6 infection after drug-induced hypersensitivity syndrome (DIHS)

Nakamura, Yuki, Miyashita, Kazuya, Onmori, Rie, Miyagawa, Fumi, Azukizawa, Hiroaki, Asada, Hideo

Journal:

Journal of Dermatological Science

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

39

The assessment of vascularity in subcutaneous tumors by ultrasonography

Shobatake, Chinatsu, Hirai, Toshiko, Ogawa, Kohei, Miyagawa, Fumi, Azukizawa, Hiroaki, Asada, Hideo

Journal:

Journal of Dermatological Science

Year:

2017

Language:

english

File:

PDF, 60 KB

english, 2017

40

Up-regulation of HHV-6 microRNAs in the serum of DIHS/DRESS patients

Miyashita, Kazuya, Miyagawa, Fumi, Nakamura, Yuki, Onmori, Rie, Azukizawa, Hiroaki, Asada, Hideo

Journal:

Journal of Dermatological Science

Year:

2017

Language:

english

File:

PDF, 58 KB

english, 2017

41

Evaluation of in-vitro diagnostic methods for identifying the culprit drugs in drug hypersensitivity

Kato, Kenichi, Azukizawa, Hiroaki, Hanafusa, Takaaki, Nakagawa, Yukinobu, Katayama, Ichiro

Journal:

Journal of Dermatological Science

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

42

First Japanese case report of atypical Spitz tumor with an ALK rearrangement

Ogawa, Kohei, Fukumoto, Takaya, Azukizawa, Hiroaki, Takeda, Maiko, Asada, Hideo

Journal:

The Journal of Dermatology

Year:

2017

Language:

english

File:

PDF, 506 KB

english, 2017

43

Development of novel double-decker microneedle patches for transcutaneous vaccine delivery

Ono, Akihiko, Azukizawa, Hiroaki, Ito, Sayami, Nakamura, Yuki, Asada, Hideo, Quan, Ying-Shu, Kamiyama, Fumio, Katayama, Ichiro, Hirobe, Sachiko, Okada, Naoki

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

44

Impact of Jumihaidokuto (Shi-Wei-Bai-Du-Tang) on treatment of chronic spontaneous urticaria: A randomized controlled study

Murota, Hiroyuki, Azukizawa, Hiroaki, Katayama, Ichiro

Journal:

Chinese Journal of Integrative Medicine

Year:

2017

Language:

english

File:

PDF, 436 KB

english, 2017

45

A case of symptomatic primary biliary cirrhosis complicated by Behçet' s disease which emerged with joint swelling

Sakane, Sadatsugu, Miyagi, Takuya, Azukizawa, Hiroaki, Sakamori, Ryotaro, Yakushijin, Takayuki, Hikita, Hayato, Oze, Tsugiko, Kamada, Yoshihiro, Yoshida, Yuichi, Tatsumi, Tomohide, Ohkawa, Kazuyoshi,

Journal:

Year:

2015

File:

PDF, 937 KB

2015

46

First Japanese case of atypical Spitz tumor exhibiting ROS1 rearrangement

Mitsui, Yasuhiro, Ogawa, Kohei, Takeda, Maiko, Nakanishi, Takashi, Azukizawa, Hiroaki, Asada, Hideo

Journal:

The Journal of Dermatology

Year:

2018

Language:

english

File:

PDF, 398 KB

english, 2018

47

Anti-PL-12 antibody-positive antisynthetase syndrome with recurrent digital ulcers

Miyagawa, Fumi, Azukizawa, Hiroaki, Mimori, Tsuneyo, Asada, Hideo

Journal:

The Journal of Dermatology

Year:

2018

Language:

english

File:

PDF, 205 KB

english, 2018

48

Psoriatic Arthritis Complicating Systemic Sclerosis: Possible Involvement of M2 Macrophages

Yamaoka, Toshifumi, Inoue, Tomoko, Kitaba, Shun, Yokomi, Akinori, Azukizawa, Hiroaki, Terao, Mika, Murota, Hiroyuki, Higashiyama, Mari, Katayama, Ichiro

Journal:

Annals of Dermatology

Year:

2015

Language:

english

File:

PDF, 532 KB

english, 2015

49

Revival of favus in Japan caused by Trichophyton schoenleinii

Iwasa, Kentaro, Ogawa, Kohei, Azukizawa, Hiroaki, Tanabe, Hiroshi, Iwanaga, Tomoyuki, Anzawa, Kazushi, Mochizuki, Takashi, Asada, Hideo

Journal:

The Journal of Dermatology

Year:

2019

Language:

english

File:

PDF, 581 KB

english, 2019

50

Facial pustules due to drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms may histopathologically mimic eosinophilic pustular folliculitis: A case report

Ogawa, Kohei, Mitsui, Yasuhiro, Miyamoto, Suzuka, Nakamura-Nishimura, Yuki, Nakanishi, Yukiko, Azukizawa, Hiroaki, Asada, Hideo

Journal:

Journal of Cutaneous Pathology

Year:

2019

File:

PDF, 54.71 MB

2019

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